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Biphasic composition = Smooth surface

In HICE® cross-linking technology, small particles of cross-linked HA fill the void between the large main particles, resulting in smoother surface* on the correction areas and consistent smooth injection *Plast Reconstr Surg Glob Open 2020;8:e2648

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Cross-linking Efficiency = Superior Elasticity

HICE® cross-linking technology offers the highest elasticity and deformation resistance. This is realized by the highest G Prime (G’=298 Pa) and the highest cross-linking ratio (CrR=30%)* among all wrinkle correction HA fillers *Prime Journal, 2019;9(2):73-76

Enzymatic Resistance = Extended Longevity

HICE® cross-linking technology provides extended longevity due to the high enzymatic resistance. This is realized by the superior cross-linking efficiency (CrR=30%)* that provides a sustainable cohesivity Ref. Plast Reconstr Surg Glob Open 2020;8: e2648

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